Pittsburgh, March 1, 2004 -- The following research projects were awarded grants by The Pittsburgh Foundation. These projects represent state-of-the-art science initiatives that will hopefully be major scientific findings in the future. One of the Copeland Fund's missions is to fund pilot projects that are promising for potential future extramural funding such as the National Institues of Health (NIH).

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Title: Identification of Human Glioma Rejection Antigen-Tcell Epitopes
Principal Investigator: Naruo Kuwashima, MD

Title: In vivo delivery of shRNA for antiangiogenesis based brain tumor gene therapy
Principal Investigator: Kevin Walter, MD

Title: Neural Stem Cell Therapy for Traumatic Brain Injury: Functional Outcomes and Cell Differentiation
Principal Investigator: Anthony Harris, MD, PhD

Title: Human Bone Marrow-Derived Novel Cellular Vehicle for Brain Tumor Gene Therapy
Principal Investigator: Tsukasa Sakaida, MD

Title: Dopamine and DARPP-32 signaling mechanisms following traumatic brain injury in rats
Principal Investigator: Margaret Wilson, MD

Title: Effect of Acupuncture on Traumatic Brain Injury (TBI) in Rats
Principal Investigator: Hong Qu Yan, MD, PhD

Title: The effect of FiO2 elevation on local brain tissue oxygenation (PbtO2) and oxidative stress in patients with severe TBI
Principal Investigator: Ava Puccio

Title: Adrenergic Activation and Cerebral Ischemia After SAH
Principal Investigator: Edwin Nemoto, PhD

Title: Suppression of Astrocytoma Cell Invasive Migration Via Competitive Peptide Inhibition of Akt/GSK3/GS Mediated Energy Metabolism
Principal Investigator: Marie Beckner

Title: Dendritic Cell-Based Cytokine Gene Immunotherapy for Central Nervous System (CNS) Tumors
Principal Investigator: Hideho Okada, PhD