R. Mark Richardson, MD, PhD, FAANSAssistant Professor
Director, Adult Epilepsy and Movement Disorders Surgery
Director, Brain Modulation Laboratory
Faculty Member, Center for the Neural Basis of Cognition
R. Mark Richardson, MD, PhD, FAANS, is director of Epilepsy and Movement Disorders Surgery at UPMC Presbyterian.
Dr. Richardson received his undergraduate education at the University of Virginia. He completed his medical and doctoral education in the MD/PhD program at the Medical College of Virginia, where his interest in adult neurogenesis led to an NIH National Research Service Award.
Prior to joining the faculty at the University of Pittsburgh in 2011, Dr. Richardson completed neurosurgical residency at the University of California San Francisco where he received specialized training in epilepsy neurosurgery, deep brain stimulation, and brain mapping during awake craniotomies. Additionally, he received an NIH National Research Service Award to study gene therapy delivery to the brain.
Dr. Richardson’s clinical specialization is comprehensive epilepsy surgery and deep brain stimulation for movement disorders. At UPMC, he created one of the first interventional-MRI DBS programs in the nation, and the only such program in Pennsylvania. Similarly, he recently became one of the first neurosurgeons in the United States to use robotics in both DBS and epilepsy surgery. He is principal investigator for the AADC gene therapy clinical trial for Parkinson disease (PD) at UPMC, one of only three institutions in the country currently performing gene therapy for PD. His additional clinical expertise includes intraoperative mapping to preserve brain function, including language, in patients who are awake during epilepsy and tumor surgery.
Please also visit Dr. Richardson's Facebook page.
Specialized Areas of Interest
Epilepsy surgery (including laser thermal ablation and robotic-assisted stereo-EEG), deep brain stimulation (including asleep DBS) for movement disorders and OCD, gene therapy, awake surgery in eloquent brain areas.
American Board of Neurological Surgeons
Professional Organization Membership:
American Association of Neurological Surgeons
American Association of Stereotactic and Functional Neurosurgery
American Epilepsy Society
American Society for Neural Transplantation and Repair
Congress of Neurological Surgeons
International Movement Disorders Society
Society for Neuroscience
Education & Training
BA, University of Virginia, 1997
MD/PhD, Medical College of Virginia, 2005
Fellowship, University of California San Francisco Postdoctoral Fellowship, 2010
Residency, University of California San Francisco Neurological Surgery, 2011
Honors & Awards
Faculty Teaching Award, Department of Neurological Surgery, 2013
Pittsburgh’s Best Doctors, Pittsburgh Magazine, 2016
Lee PS, Pardini J, Hendrickson R, Destefino V, Popescu A, Ghearing G, Antony A, Pan J, Bajic A, Wagner D, Richardson RM. Short-term neurocognitive outcomes following anterior temporal lobectomy. Epilepsy Behav 62:140-146, 2016.
Aminoff EM, Li Y, Pyles JA, Ward M, Richardson RM, Ghuman AS. Associative hallucinations result from stimulating left ventromedial temporal cortex. Cortex 83:139-44, 2016.
Hirshorn EA , Li Y, Ward MJ, Richardson RM, Fiez J, Ghuman AS. Decoding and disrupting left mid-fusiform gyrus activity during word reading. Proc Natl Acad Sci USA 113(29):8162-7, 2016.
Kondylis ED, Randazzo MJ, Alhourani A, Lipski WJ, Wozny TA, Ghuman AS, Turner RS, Crammond DJ, Richardson RM. Movement-related dynamics of cortical oscillations in Parkinson’s disease and essential tremor. Brain 139(Pt 8):2211-23, 2016.
Modo M, Hitchens TK, Liu JR, Richardson RM. Detection of aberrant hippocampal mossy fiber connections – ex vivo mesoscale diffusion MRI and micro-tractography with histological validation in a patient with uncontrolled temporal lobe epilepsy. Hum Brain Mapp 37(2):780-95, 2015.
Randazzo MJ, Kondylis ED, Alhourani A, Wozny TA, Lipski WJ, Crammond DJ, Richardson RM. Three-Dimensional Localization of Cortical Electrodes in Deep Brain Stimulation Surgery from Intraoperative Fluoroscopy. Neuroimage 125:515-521, 2015.
Alhourani A, McDowell MM, Randazzo M, Wozny T, Kondylis E, Lipski WJ, Beck S, Karp JF, Ghuman AS, Richardson RM. Network Effects of Deep Brain Stimulation. J Neurophysiol 114(4):2105-17, 2015.
Ghuman AS, Brunet NM, Li Y, Konecky RO, Pyles JA, Walls SA, Destefino V, Wang W, Richardson RM. Dynamic encoding of face information in the human fusiform gyrus. Nature Commun 8;5:5672, 2014.
Kondylis ED, Wozny TA, Lipski WJ, Popescu A, DeStefino VJ, Esmaeili B, Raghu VK, Bagic A, Richardson RM. (2014) Detection of high-frequency oscillations by hybrid depth electrodes in standard clinical intracranial EEG recordings. Front Neurol 6;5:149, 2014.
Lipski WJ, DeStefino VJ, Stanslaski SR, Antony AR, Crammond DJ, Cameron JL, Richardson RM. Sensing-Enabled Hippocampal Deep Brain Stimulation In Idiopathic Nonhuman Primate Epilepsy. J Neurophysiol 113(4):1051-62, 2015.
A complete list of Dr. Richardson's publications can be reviewed through the National Library of Medicine's publication database.
Innovation in brain imaging
February 16, 2017
Erie hospital joins Parkinson's research project
January 26, 2017
Brain Surgery Option Now For Patients Crippled By Severe OCD
August 31, 2016
CBS TV-2, New York
Epilepsy Research Leads To New Insights Into How Our Brains Read
August 16, 2016
WESA Radio Pittsburgh Tech Report
Deep Brain Stimulation Could Help Patients With Severe OCD
July 13, 2016
KDKA-TV Evening News
Parkinson’s patients find relief through surgery
June 2, 2016
Oregon's The Bulletin
Neurobiology of Deep Brain Stimulation
April 27, 2016
Journal of Neurophysiology Podcasts
Deep-brain stimulation helps Erie Parkinson's patients
March 26, 2016
Pitt professor's gene therapy trial holds promise for Parkinson's patients
February 29, 2016
Local Doctor Leads Study Of Gene Therapy Treatment For Parkinson’s Patients
February 18, 2016
Neurotechnology offers new solutions to treating brain diseases
January 26, 2016
Neurosurgeons using laser technology to eradicate brain tumors
November 9, 2015
McCandless woman 1st in region with implant aimed at halting seizures
August 2, 2015
Richardson Discusses Epilepsy
June 8, 2015
KDKA Radio Morning News
Functional neurosurgery for improving quality of life (pdf)
Allegheny County Medical Society Bulletin
UPMC procedure offers hope for severe OCD cases
August 11, 2014
Health Beat: Parkinson's: Stop the shaking
June 5, 2014
WFMZ-TV 69 (Lehigh Valley, Pa.)
Parkinson’s: Stop the shaking
May 28, 2014
WWSB-TV 7 (Sarasota, Fla.)
Breakthrough Parkinson's treatment stops the shaking
May 27, 2014
WNDU-TV (South Bend, Ind.)
Pittsburgh chef Pais honored at James Beard fundraiser dinner at Art Institute
May 27, 2014
Parkinson’s: Stop The Shaking
May 14, 2014
NewsChannel5.com (Nashville, Tenn.)
New technique minimizes tremors in Parkinson's patient
May 4, 2014
News4Jax.com (Jacksonville, Fla.)
Richardson Discusses Parkinson's and DBS
April 30, 2014
KDKA Radio Morning News
September 23, 2013
'Brain pacemaker' may slow effects of Alzheimer's
March 19, 2013
A return to normalcy for Shadyside chef Toni Pais
March 17, 2013
August 15, 2012
UPMC OnTopic Discussions
Adult Epilepsy Surgery
Dr. Richardson discusses the benefits of epilepsy surgery for adult patients.