Charles E. Romero, MD, joined the University of Pittsburgh in 2013 as a vascular and CAST-accredited neuroendovascular surgeon-neurologist specializing in the treatment of vessel diseases of the brain, including aneurysms, stroke, carotid artery stenosis, arteriovenous malformations and fistulas, cavernomas, and intracerebral hemorrhage using minimally invasive techniques. As director of UPMC Hamot’s comprehensive stroke program, Dr. Romero is responsible for leading a team that provides stroke care, develops policies and procedures, and ensures the highest quality of care. His team is also working vigorously to improve patient outcomes and educate patients and their families about cerebrovascular disease.
Dr. Romero completed his undergraduate work at Rutgers University. He received his medical degree from the Universidad Autonoma de Guadalajara School of Medicine. He then completed an academic year of supervised clinical education and fifth pathway certification at New York Medical College. Dr. Romero completed the neurology residency program at Tufts Medical Center in Boston followed by fellowships in both stroke and interventional neuroradiology at Lahey Clinic Hospital & Medical Center in Burlington, Massachusetts.
Dr. Romero has published numerous papers and book chapters, participated in clinical trials, and he has lectured at national conferences, medical institutions, and academic gatherings covering endovascular stroke care, groundbreaking research, and preventive health care. His research interests include clinical outcomes in the treatment of cerebrovascular disease and stroke prevention.
Specialized Areas of Interest
Board Certifications
American Board of Psychiatry and Neurology
Hospital Privileges
Professional Organization Membership
Education & Training
- BS, Biology, Rutgers University, 1992
- Postbaccalaureate Premedical Certification, Columbia University, 1994
- MD, Universidad Autonoma de Guadalajara School of Medicine, 1999
- Fifth Pathway Certification, New York Medical College, 2000
- Residency, Neurology, Tufts Medical Center, 2005
- Fellowship, Stroke, Lahey Clinic Hospital & Medical Center, 2006
Honors & Awards
- Patient Awards, U.S. News & World Report, 2011
Research Activities
•Multicenter, international, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of ischemic stroke in male and female participants aged 18 years and older after an acute non-cardioembolic ischemic stroke or high-risk TIA (OCEANIC-STROKE)
Phase 3 program of the Oral faCtor Eleven A iNhibitor asundexLan as novel anti-thrombotiC STROKE study.
Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)
Two-stage Phase III trial randomizing subjects with stroke attributed to 70-99% intracranial atherosclerotic stenosis to 1. ticagrelor + aspirin, 2. low dose rivaroxaban + aspirin, 3. clopidogrel + aspirin.
Protection against Emboli during caRotid artery stenting using a 3-in-1 delivery system comprised oF a pOst-dilation balloon, integRated eMbolic filter, and A Novel Carotid stEnt II (PERFORMANCE II)
Prospective, single-arm, multicenter clinical trial to evaluate the safety and effectiveness of the Neuroguard IEP System for the treatment of carotid artery stenosis.
Media Appearances
Ironman triathlete from Girard survives rare, life-threatening stroke
GoErie.com
May 31, 2022
Stroke care and awareness in the time of COVID-19
GoErie.com
May 3, 2020
UPMC Hamot certified as stroke center
GoErie.com
August 14, 2018
Not all stroke centers the same: Letters to the editor
GoErie.com
June 28, 2015