Current clinical trials run through the UPMC Stroke Institute include (more detailed info on these trials will be included here soon):
Ischemic Stroke Studies
- Carotid Revascularization for Primary Prevention of Stroke (CREST 2) Trial
- Platelet-Oriented inhibition in New TIA and minor ischemic stroke (POINT) Trial
- Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial
- A Study of the Efficacy and Safety of Activase (Alteplase) in Patients with Mild Stroke (PRISMS)
- Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) Trial
- Safety Evaluation of 3K3A-APC in Ischemic Stroke (NN104 RHAPSODY)
- SolitaireTM FR as Primary Treatment for Acute Ischemic Stroke (SWIFT PRIME)
- GORE HELEX Septal Occluder / GORE Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients- The Gore REDUCE Clinical Study
- A Study of Modified Stem Cells in Stable Ischemic Stroke
- Study to Examine the Effects of MultiStem in Ischemic Stroke
- Computed Tomography Perfusion (CTP) to Predict Response to Recanalization in Ischemic Stroke Project (CRISP)
- Trevo and Medical Management versus Medical Management Alone in Wakeup and Late Presenting Strokes (DAWN)
- Patient-centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Trial
- Glyburide Advantage in Malignant Edema and Stroke (GAMES) Trial
Hemorrhagic Stroke/Aneurysm Studies
- Intra-arterial Vasospasm Trial (IVT)
- Ultra 3 Registry
- Low Profile Visualized Intraluminal Support Device (LVIS) Study
- BARREL Vascular Reconstruction Device Study
- Clot Lysis: CLEAR III Trial
- STOP-IT (Using Spot-sign to predict hematoma growth)
- Anti-hypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-II) Trial
- Minimally Invasive Surgery Plus rt-PA for Intracerebral Hemorrhage Evacuation (MISTIE-III) Trial